Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy.
Chen MaLudi ZhangTing HeHuiying CaoXiongzhao RenChenhui MaJiale YangRuimin HuangGuoyu PanPublished in: Stem cell research & therapy (2021)
In brief, Raman spectroscopy was successfully employed to identify different stages of ProliHHs during dedifferentiation process. The approach can simultaneously trace multiple changes of cellular components from somatic cells to progenitor cells.
Keyphrases
- raman spectroscopy
- cell therapy
- single cell
- induced apoptosis
- endothelial cells
- stem cells
- mesenchymal stem cells
- cell cycle arrest
- rna seq
- endoplasmic reticulum stress
- induced pluripotent stem cells
- liver injury
- heavy metals
- gene expression
- copy number
- cell death
- signaling pathway
- pluripotent stem cells
- cell proliferation
- drug induced
- dna methylation
- bone marrow
- genome wide
- risk assessment