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Multi-dimensional analysis identified rheumatoid arthritis-driving pathway in human T cell.

Masaru TakeshitaKatsuya SuzukiYasushi KondoRimpei MoritaYuumi OkuzonoKeiko KogaYoshiaki KassaiKanae GamoMaiko TakiguchiRina KurisuHideyuki MototaniYukihiko EbisunoAkihiko YoshimuraTsutomu Takeuchi
Published in: Annals of the rheumatic diseases (2019)
Our multi-dimensional investigation identified disease relevant T-cell subsets and gene signatures deeply involved in pathogenesis of RA. These findings could aid in our understanding of essential roles of T cells in RA and will facilitate to development better diagnostic and therapeutic interventions.
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