Repeated sprint exercise in hypoxia stimulates HIF-1-dependent gene expression in skeletal muscle.
Roberto Carlos NavaZachary McKennaZachary FennelQuint BerkemeierJeremy DucharmeFlávio de Castro MagalhãesFabiano Trigueiro AmorimChristine MermierPublished in: European journal of applied physiology (2022)
Repeated sprint exercise in hypoxia upregulates some genes involved in glycolytic metabolism, mitochondrial turnover, and oxygen transport. HIF-1α is necessary for the expression of these genes in skeletal muscle cells.
Keyphrases
- skeletal muscle
- high intensity
- endothelial cells
- resistance training
- gene expression
- induced apoptosis
- insulin resistance
- poor prognosis
- oxidative stress
- cell cycle arrest
- dna methylation
- physical activity
- body composition
- genome wide
- endoplasmic reticulum stress
- bone mineral density
- binding protein
- type diabetes
- metabolic syndrome
- pi k akt