Voltage-Dependent Anion Channel 1 Expression in Oral Malignant and Premalignant Lesions.

Irit AllonJacob PetteshAlejandro LivoffMark ShlapoberskyOded NahlieliEli Michaeli

Published in: Diagnostics (Basel, Switzerland) (2023)

Oral squamous cell carcinoma and epithelial dysplasia tissues demonstrated decreased VDAC1 protein expression if compared to fibrous hyperplasia samples, but were not different from each other, suggesting that the involvement of VDAC1 in oral carcinogenesis is an early stage event, regulating cells to live or die.

Keyphrases

early stage
induced apoptosis
poor prognosis
gene expression
cell cycle arrest
endoplasmic reticulum stress
ionic liquid
cell proliferation
binding protein
cell death
neoadjuvant chemotherapy
signaling pathway
radiation therapy
pi k akt
rectal cancer