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Characteristics and treatment outcomes of newly diagnosed epilepsy in older people: A 30-year longitudinal cohort study.

Bshra Ali A AlsfoukHaris HakeemZhibin Chen MBiostatMatthew WaltersMartin J BrodiePatrick Kwan
Published in: Epilepsia (2020)
There was often a long interval between seizure onset and the initiation of treatment in older people with new-onset epilepsy, although the majority responded well to ASM treatment. Brain imaging showed a high rate of abnormalities. Despite the increased use of second-generation ASMs, treatment outcomes in later-onset epilepsy have not improved over time. The possible effect of aspirin on treatment response warrants further investigation.
Keyphrases
  • newly diagnosed
  • low dose
  • type diabetes
  • cardiovascular disease
  • coronary artery disease
  • cross sectional
  • brain injury
  • white matter
  • blood brain barrier
  • replacement therapy