Combined oral contraceptive use and obesity in women with polycystic ovary syndrome. A meta-analysis of randomized clinical trials.

Sebastião Freitas de MedeirosJosé Maria Soares JuniorMatheus Antonio Souto de MedeirosAna Karine Lin Winck YamamotoCindy Lin Winck de MedeirosAnna Bethany da Silva CarvalhoMárcia Marly Winck YamamotoEdmund Chada Baracat

Published in: Archives of gynecology and obstetrics (2024)

Combined oral contraceptives with different formulations might increase fat mass accumulation in women with PCOS. Lipids may also be increased in PCOS users. Because some concerns about the quality and heterogeneity identified in various RCTs, caution should be taken before a definitive conclusion regarding the use of COCs and obesity.

Keyphrases

polycystic ovary syndrome
insulin resistance
adipose tissue
metabolic syndrome
high fat diet induced
weight loss
type diabetes
weight gain
skeletal muscle
fatty acid
squamous cell carcinoma
body mass index
pregnancy outcomes
radiation therapy
pregnant women
cervical cancer screening