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Genetic and environmental factors affecting the expression of α-gliadin canonical epitopes involved in celiac disease in a wide collection of spelt (Triticum aestivum ssp. spelta) cultivars and landraces.

Benjamin DjoudalbayePierre BertinLouis HautierYordan MuhovskiEmmanuelle EscarnotDominique Mingeot
Published in: BMC plant biology (2018)
The results obtained in this work showed that the CD-related epitope expression greatly fluctuated among the spelt accessions studied. This expression was not correlated to the epitope genomic occurrence and environmental factors had almost no influence on the amount of epitope transcripts.
Keyphrases
  • poor prognosis
  • celiac disease
  • binding protein
  • risk assessment
  • monoclonal antibody
  • gene expression
  • genome wide
  • climate change
  • human health