Role of nucleus accumbens microRNA-181a and MeCP2 in incubation of heroin craving in male rats.

Wenjin XuQingxiao HongZi LinHong MaWeisheng ChenDingding ZhuangHuaqiang ZhuMiaojun LaiDan FuWenhua ZhouHuifen Liu

Published in: Psychopharmacology (2021)

Results indicate that incubation of heroin craving is mediated in part by time-dependent decreases in NAc miR181a expression that leads to time-dependent increases in MeCP2 expression. Our data suggest that NAc miR-181a and MeCP2 contribute to incubation of heroin craving.

Keyphrases

poor prognosis
long non coding rna
cell proliferation
transcription factor
long noncoding rna
binding protein
big data
data analysis