Sex Differences in Insulin Sensitivity are Related to Muscle Tissue Acylcarnitine But Not Subcellular Lipid Distribution.
Josiane L BroussardLeigh PerreaultEmily MaciasSean A NewsomKathleen HarrisonHai Hoang BuiPaul MilliganKenneth D RothTravis NemkovAngelo D'AlessandroJoseph T BrozinickBryan C BergmanPublished in: Obesity (Silver Spring, Md.) (2021)
These data reveal novel sex-specific associations between lipid species involved in the coupling of mitochondrial fatty acid transport, β-oxidation, and tricarboxylic acid cycle flux that may provide therapeutic targets to improve insulin sensitivity.