Molecular Imaging of Melanoma VEGF-expressing Tumors through [99mTc]Tc-HYNIC-Fab(Bevacizumab).

Ximena Camacho Carolina Perroni Lucía Alfaya Mirel Cabrera Marcos Tassano María Fernanda García Marcelo Fernández Ana Laura Reyes Andrea Paolino Eduardo Savio Hugo E Cerecetto Pablo Cabral Juan Pablo Gambini

Published in: Anti-cancer agents in medicinal chemistry (2024)

We present the development and evaluation of [99mTc]Tc-HYNIC-Fab(bevacizumab), a novel molecular VEGF expression imaging agent that may be used for precision medicine in melanoma and potentially in other VEGF-expressing tumors.

Keyphrases

vascular endothelial growth factor
endothelial cells
poor prognosis
metastatic colorectal cancer
high resolution
binding protein
photodynamic therapy