Is there an optimal timing between radiotherapy and surgery to reduce wound complications in metastatic spine disease? A systematic review.
Aravind KumarSirisha MadhuHussain BohraNaveen PanditaSamuel Sherng Young WangKeith Gerard LopezJiong Hao TanBalamurugan A VellayappanPublished in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2020)
Evidence is insufficient to draw definitive conclusion about optimal RT-surgery interval. However, based on published literature and expert opinions, we conclude that an interval of 2 weeks, the minimum being 7 days, is optimum between RT-surgery or vice versa; this can be reduced further by postop-stereotactic body RT. If RT-surgery window is > 12 months, wound-complications rise. Postop-RT has fewer wound complications versus preop-RT.