Clinical Significance of the Immunohistochemical Expression of Histone Deacetylases (HDACs)-2, -4, and -5 in Ovarian Adenocarcinomas.

Georgia LevidouDimitrios ArsenakisDimitrios I BolovisRoxanne MeyerCosima V M BruckerThomas PapadopoulosStamatios Theocharis

Published in: Biomedicines (2024)

These findings suggest a differential expression among HDAC-2, -4, and -5 in ovarian adenocarcinomas in terms of immunolocalization, positivity rate, and associations with clinicopathological parameters, providing evidence for a potential role in the pathobiology of EOC.

Keyphrases

poor prognosis
dna methylation
squamous cell
histone deacetylase
binding protein
gene expression
long non coding rna