Early detection and prognosis evaluation for hepatocellular carcinoma by circulating tumour DNA methylation: A multicentre cohort study.

De-Zhen GuoAo HuangYing-Chao WangShuang ZhouHui WangXiang-Lei XingShi-Yu ZhangJian-Wen ChengKe-Hui XieQi-Chang YangCheng-Cheng MaQing LiYan ChenZhi-Xi SuJia FanRui LiuXiao-Long LiuJian ZhouXin-Rong Yang

Published in: Clinical and translational medicine (2024)

HepaAiQ, a noninvasive qMSP assay, was developed to accurately measure HCC-specific DMRs and shows great potential for the diagnosis, detection and prognosis of HCC, benefiting at-risk populations.

Keyphrases

dna methylation
high throughput
gene expression
study protocol
label free
randomized controlled trial
real time pcr
double blind
risk assessment