Evaluate the safety and efficacy of dura sealant patch in reducing cerebrospinal fluid leakage following elective cranial surgery (ENCASE II): study protocol for a randomized, two-arm, multicenter trial.
Andrew P CarlsonEmma M H SlotTristan P C van Doormaalnull nullE H J VoormolenJ W DankbaarP DepauwB BrouwersM R GermansE BaertJ VandersteeneC F FreyschlagJ FreyschlagC ThoméF ZengaF PennerA AbdulazimM SabelM RappT BeezM ZuccarelloE SauvageauK AbdullahB WelchD LangerJ EllisA DehdashtiJ VanGompelB BendokK ChaichanaJ LiuA DoganM K LimM G HaydenPublished in: Trials (2022)
This trial will evaluate whether LIQOSEAL is non-inferior to control as a means of reducing CSF leakage and safety TRIAL REGISTRATION: ClinicalTrials.gov NCT04086550 . Registered on 11 September 2019.