VEGF Expression in Umbilical Cord MSC Depends on the Patient's Health, the Week of Pregnancy in Which the Delivery Took Place, and the Body Weight of the Newborn - Preliminary Report.
Karolina BieńkoMonika LeszczMarta WięckowskaJustyna BiałekAlicja PetniakRafał SzymanowskiAgnieszka WilińskaBartosz PiszczArkadiusz KrzyżanowskiAnna KwaśniewskaBartosz Jan PłachnoPaulina Gil-KulikJanusz KockiPublished in: Stem cells and cloning : advances and applications (2023)
Probably due to hypoxia (caused, for example, by hypothyroidism or hypertension), the MSCs found in the umbilical cord may react with an increased expression of VEGF and a compensatory increase in the amount of secreted factor, the aim of which is, i.a., vasodilation and increase of blood supply to the fetus through the umbilical vessels.