Loss of STING expression is prognostic in non-small cell lung cancer.

Zoltan LohinaiDavid DoraCharles CaldwellChristopher J RivardKenichi SudaHui YuGareth RivallandKim EllisonLeslie RozeboomRafal DziadziuszkoPaul MitchellThomas JohnInigo S MillanShengxiang RenFred R Hirsch

Published in: Journal of surgical oncology (2022)

STING is ubiquitously expressed in NSCLC and associated with T cell function genes, AC histology, EGFR, and KRAS mutations and improved overall survival.

Keyphrases

small cell lung cancer
poor prognosis
epidermal growth factor receptor
advanced non small cell lung cancer
genome wide
tyrosine kinase
brain metastases
free survival
binding protein
wild type
genome wide identification
dna methylation