ASPRE trial: risk factors for development of preterm pre-eclampsia despite aspirin prophylaxis.
L ShenRaigam Jafet Martínez-PortillaDaniel Lorber RolnikLiona Chiu Yee PoonPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)
In pregnancies at high risk of preterm PE identified by screening at 11-13 weeks' gestation using the FMF algorithm, a very high-risk result (estimated risk ≥ 1 in 50), compared to an estimated risk of 1 in 51 to 1 in 100, chronic hypertension, compared to no chronic hypertension, and low PlGF concentration (< 0.712 MoM), compared to PlGF ≥ 0.712 MoM, were associated with the development of preterm PE despite aspirin prophylaxis. © 2021 International Society of Ultrasound in Obstetrics and Gynecology.
Keyphrases
- gestational age
- preterm birth
- low birth weight
- blood pressure
- low dose
- preterm infants
- cardiovascular events
- antiplatelet therapy
- magnetic resonance imaging
- clinical trial
- deep learning
- study protocol
- randomized controlled trial
- phase iii
- cardiovascular disease
- atrial fibrillation
- percutaneous coronary intervention
- acute coronary syndrome
- computed tomography
- arterial hypertension
- contrast enhanced ultrasound