Sex Related Differences in the Complex Relationship between Coffee, Caffeine and Atrial Fibrillation.
Francesca CoppiValentina BucciarelliGiorgia SinigagliaGiada ZaniniValentina SelleriMilena NasiMarcello PintiSabina GallinaAnna Vittoria MattioliPublished in: Nutrients (2023)
This literature review aims to explore the data of articles published on the association between coffee, caffeine and atrial fibrillation and to analyze any differences between the two sexes. Several factors influence this complex relationship; genetic, environmental and psychosocial factors come into play in the pathophysiology of atrial fibrillation. These factors are expressed differently in women and men. However, the analysis of the literature has shown that comparison works between the two sexes are extremely rare. Most population-based and prospective studies either analyze aggregated data or focus on exclusively male or female populations. This results in a lack of information that could be useful in the prevention of and treatment approach to atrial fibrillation. It is necessary to deepen this issue with dedicated studies.
Keyphrases
- atrial fibrillation
- catheter ablation
- oral anticoagulants
- left atrial
- left atrial appendage
- direct oral anticoagulants
- heart failure
- percutaneous coronary intervention
- electronic health record
- systematic review
- healthcare
- big data
- case report
- case control
- randomized controlled trial
- left ventricular
- gene expression
- dna methylation
- mitral valve
- pregnant women
- skeletal muscle
- climate change
- deep learning
- meta analyses