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Induced pluripotent stem cells reduce neutrophil chemotaxis via activating GRK2 in endotoxin-induced acute lung injury.

Vincent Yi-Fong SuShih-Hwa ChiouChi-Shiuan LinWei-Chih ChenWen-Kuang YuYen-Wen ChenCheng-Yu ChenKuang-Yao Yang
Published in: Respirology (Carlton, Vic.) (2017)
iPSCs reduce neutrophil chemotaxis in endotoxin-induced ALI. These effects are associated with an enhancement of GRK2 activity and reduction of CXCR2 expression.
Keyphrases
  • induced pluripotent stem cells
  • high glucose
  • diabetic rats
  • poor prognosis
  • lipopolysaccharide induced
  • oxidative stress
  • lps induced
  • inflammatory response