Chemical Composition and Antibacterial Activity of Liquid and Volatile Phase of Essential Oils against Planktonic and Biofilm-Forming Cells of Pseudomonas aeruginosa .
Malwina BrożynaJustyna PalecznyWeronika KozłowskaDaria Ciecholewska-JuśkoAdam ParfieńczykGrzegorz ChodaczekAdam F JunkaPublished in: Molecules (Basel, Switzerland) (2022)
Pseudomonas aeruginosa is an opportunistic pathogen causing life-threatening, hard-to-heal infections associated with the presence of a biofilm. Essential oils (EOs) are promising agents to combat pseudomonal infections because of the alleged antimicrobial activity of their volatile fractions and liquid forms. Therefore, the purpose of this paper was to evaluate the antibacterial efficacy of both volatile and liquid phases of seven EOs (thyme, tea tree, basil, rosemary, eucalyptus, menthol mint, lavender) against P. aeruginosa biofilm and planktonic cells with the use of a broad spectrum of analytical in vitro methods. According to the study results, the antibacterial activity of EOs in their liquid forms varied from that of the volatile fractions. Overall, liquid and volatile forms of rosemary EO and tea tree EO displayed significant antibiofilm effectiveness. The outcomes indicate that these particular EOs possess the potential to be used in the therapy of P. aeruginosa infections.
Keyphrases
- pseudomonas aeruginosa
- biofilm formation
- cystic fibrosis
- induced apoptosis
- gas chromatography
- ionic liquid
- candida albicans
- staphylococcus aureus
- acinetobacter baumannii
- cell cycle arrest
- randomized controlled trial
- silver nanoparticles
- systematic review
- essential oil
- mass spectrometry
- type diabetes
- escherichia coli
- stem cells
- endoplasmic reticulum stress
- signaling pathway
- metabolic syndrome
- mesenchymal stem cells
- high resolution
- skeletal muscle
- cell proliferation
- liquid chromatography
- cell therapy