COCO enhances the efficiency of photoreceptor precursor differentiation in early human embryonic stem cell-derived retinal organoids.

Deng PanXi-Xi XiaHeng ZhouSi-Qian JinYang-Yan LuHui LiuMei-Ling GaoZi-Bing Jin

Published in: Stem cell research & therapy (2020)

Tracing with the CRX-reporter system showed that in retinal organoids derived from human pluripotent stem cells, COCO increased the differentiation efficiency of photoreceptor precursors and cones.

Keyphrases

pluripotent stem cells
induced pluripotent stem cells
endothelial cells
optical coherence tomography
diabetic retinopathy
crispr cas