Elevated Ki-67 (MIB-1) expression as an independent predictor for unfavorable pathologic outcomes and biochemical recurrence after radical prostatectomy in patients with localized prostate cancer: A propensity score matched study.
Seok-Soo ByunMinseung LeeSung Kyu HongHakmin LeePublished in: PloS one (2019)
In our study, high Ki-67 expression was significantly related with adverse pathological and finally with worse biochemical recurrence-free survival. Further studies are needed to validate the prognostic value of Ki-67 more exactly in PCa patients.
Keyphrases
- prostate cancer
- radical prostatectomy
- free survival
- neoadjuvant chemotherapy
- poor prognosis
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- type diabetes
- binding protein
- squamous cell carcinoma
- weight loss
- locally advanced
- lymph node
- insulin resistance
- electronic health record
- drug induced
- patient reported