Preclinical evaluation and pilot clinical study of [ 68 Ga]Ga-THP-APN09, a novel PD-L1 targeted nanobody radiotracer for rapid one-step radiolabeling and PET imaging.

Xiaopan MaXin ZhouBiao HuXiaoda LiMeinan YaoLiqiang LiXue QinDaPeng LiYuan YaoXingguo HouSong LiuYan ChenZilei WangWenyuan ZhouNan LiHua ZhuBing JiaZhi Yang

Published in: European journal of nuclear medicine and molecular imaging (2023)

Clinical Trial (NCT05156515). Registered 12 December 2021.

Keyphrases

pet imaging
pet ct
positron emission tomography
clinical trial
study protocol
double blind
cancer therapy
phase ii
open label
randomized controlled trial
computed tomography
stem cells
phase iii
mesenchymal stem cells
placebo controlled