Postoperative non-steroidal anti-inflammatory drugs and anastomotic leakage after gastrointestinal anastomoses: Systematic review and meta-analysis.

Supaschin JamjittrongAkihisa MatsudaSatoshi MatsumotoTunyaporn KamonvarapitakNobuyuki SakurazawaYouichi KawanoTakeshi YamadaHideyuki SuzukiMasao MiyashitaHiroshi Yoshida

Published in: Annals of gastroenterological surgery (2019)

Results of this meta-analysis indicate that postoperative NSAID use is associated with anastomotic leakage following gastrointestinal surgeries. Caution is warranted when using NSAIDs for postoperative analgesic control in patients with gastrointestinal anastomoses.

Keyphrases

anti inflammatory drugs
patients undergoing
systematic review
rectal cancer
randomized controlled trial
neuropathic pain
spinal cord
case control