The IMPOWR Network Divided or Single Exposure Study (DOSE) Protocol: A Randomized Controlled Comparison of Once Versus Split Dosing of Methadone for the Treatment of Comorbid Chronic Pain and Opioid Use Disorder.
Greer McKendrickWill DavisMichael SklarNicole BrownEmma PattilloPatrick H FinanDenis AntoineVickie WaltersKelly E DunnPublished in: Substance use & addiction journal (2024)
Split dosing is a relatively common technique in OUD treatments; therefore, if data support this hypothesis, there is high potential for implementation.