Clinically Relevant and Minimally Invasive Tumor Surveillance of Pediatric Diffuse Midline Gliomas Using Patient-Derived Liquid Biopsy.

Eshini PanditharatnaLindsay B KilburnMariam S AboianMadhuri KambhampatiHeather Gordish-DressmanSuresh N MaggeNalin GuptaJohn S MyserosEugene I HwangCassie KlineJohn R CrawfordKatherine E WarrenSoonmee ChaWinnie S LiangMichael E BerensRoger J PackerAdam C ResnickMichael PradosSabine MuellerJavad Nazarian

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)

Our liquid biopsy approach provides a molecularly based tool for tumor characterization, and is the first to indicate clinical utility of ctDNA for longitudinal surveillance of DMGs.

Keyphrases

minimally invasive
public health
ultrasound guided
ionic liquid
high grade
low grade
cross sectional
circulating tumor