Relationship among psychotic features, benzodiazepine receptor agonists, and rehospitalization in patients with electroconvulsive therapy-responsive major depressive disorder: A retrospective 2-year observational study.
Akise UmakoshiMasahiro TakeshimaYu ItohMari YamamotoNana ShibataMasaya OgasawaraNaoko AyabeKazuo MishimaPublished in: Neuropsychopharmacology reports (2022)
Our exploratory study found no difference in the benzodiazepine receptor agonists use at the end of electroconvulsive therapy between rehospitalization and non-rehospitalization groups in patients with electroconvulsive therapy-responsive psychotic depression. Thus, the relapse-preventing effect of these agonists in psychotic depression should be investigated in future randomized controlled trials. Further research is also needed to determine whether psychotic features are associated with rehospitalization in these patients.
Keyphrases
- bipolar disorder
- major depressive disorder
- depressive symptoms
- end stage renal disease
- randomized controlled trial
- ejection fraction
- newly diagnosed
- cancer therapy
- sleep quality
- peritoneal dialysis
- clinical trial
- patient reported outcomes
- atomic force microscopy
- free survival
- mass spectrometry
- study protocol
- single molecule