Zishen Qingre Lishi Huayu Recipe May Ameliorate the Symptoms of PCOS Model Rats via Alleviating Systemic and Ovarian Inflammation.

Xin LiYao YiYunying RenYixuan ZhangChi Chiu WangChengyi LiuShuzhen LiuXiaoxuan ZhanXingxing YuRuining Liang

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2024)

This study reveals that the treatment of endocrine disorders and ovulation disorders in PCOS with ZQLHR may be closely related to the improvement of systemic and ovarian inflammation in PCOS patients, as well as the inhibition of IL-6R, IL-1β, and LOX expression in GCs, which reemphasizes the role of reducing chronic inflammatory states in the treatment of PCOS. Moreover, this study reemphasizes the correlation between multiple inflammatory mediators and IR.

Keyphrases

polycystic ovary syndrome
oxidative stress
poor prognosis
ejection fraction
newly diagnosed
insulin resistance
type diabetes
metabolic syndrome
adipose tissue
sleep quality
replacement therapy
patient reported