Upregulation of MIF as a defense mechanism and a biomarker of Alzheimer's disease.

Si ZhangJiehao ZhaoYuhu ZhangYun ZhangFang CaiLijuan WangWeihong Song

Published in: Alzheimer's research & therapy (2019)

Our study suggests that neuronal secretion of MIF may serve as a defense mechanism to compensate for declined cognitive function in AD, and increased MIF level could be a potential AD biomarker.

Keyphrases

poor prognosis
cognitive decline
innate immune
climate change