Dynamic radiation-induced imaging changes more than 20 years following gamma knife surgery.
Ai Peng TanTseng Tsai YeoHsiang Rong Clement YongBengt KarlssonPublished in: Acta neurochirurgica (2021)
Gamma knife radiosurgery (GKS), a technique which involves delivery of a high dose of radiation to a precisely defined target, has become the predominant treatment option for brain metastases (BM) because of its high effectiveness and relatively minimal toxicity. Herein, we report a case of late-onset radiation-induced edema around an asymptomatic cyst, more than 20 years after salvage GKS, with 27 years of imaging follow-up, allowing the description of the evolutionary trajectory of these relatively rare complications. Our reported case also demonstrated the benign nature of delayed cyst formation (DCF), emphasizing that observation alone is reasonable for asymptomatic patients.
Keyphrases
- radiation induced
- brain metastases
- late onset
- radiation therapy
- high dose
- small cell lung cancer
- high resolution
- end stage renal disease
- early onset
- minimally invasive
- newly diagnosed
- randomized controlled trial
- chronic kidney disease
- systematic review
- ejection fraction
- low dose
- oxidative stress
- prognostic factors
- coronary artery bypass
- peritoneal dialysis
- risk factors
- patient reported outcomes
- stem cell transplantation
- mass spectrometry
- coronary artery disease
- fluorescence imaging