LipF increases rifampicin and streptomycin sensitivity in a Mycobacterium tuberculosis surrogate.
Ana Leticia Arriaga-GuerreroCarlos E Hernández-LunaJoyce Rigal-LealRene J Robles-GonzálezLaura Adiene González-EscalanteBeatriz Silva-RamírezRoberto Mercado-HernándezJavier Vargas-VillarrealMario Bermúdez de LeónKatia Peñuelas-UrquidesPublished in: BMC microbiology (2020)
LipF expression was associated with increased RIF and STR sensitivity in mycobacteria. Reduced LipF expression may contribute to the development of RIF and STR resistance in Mycobacterium species. Our findings provide information pertinent to understanding mycobacterial drug resistance mechanisms.