Night-Shift Work Duration and Risk of Colorectal Cancer According to IRS1 and IRS2 Expression.

Yan ShiLi LiuTsuyoshi HamadaJonathan A NowakMarios GiannakisYanan MaMingyang SongDaniel NevoKeisuke KosumiMancang GuSun A KimTeppei MorikawaKana WuJing SuiKyriaki PapantoniouMolin WangAndrew T ChanCharles S FuchsJeffrey A MeyerhardtEdward GiovannucciShuji OginoEva Susanna SchernhammerReiko NishiharaXuehong Zhang

Published in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)

Although these findings need validation, rotating night shift might increase colorectal cancer risk in women with abnormal insulin receptor pathways.

Keyphrases

poor prognosis
type diabetes
sleep quality
binding protein
glycemic control
long non coding rna
metabolic syndrome