Clinical drug trials in general practice: how well are external validity issues reported?
Anja Maria BrændJørund StraandAtle KlovningPublished in: BMC family practice (2017)
The clinical setting of the trials, the selection of patients before enrolment, and co-morbidity or co-medication of participants was most commonly not reported, limiting the possibility to consider the generalizability of a trial. It may therefore be difficult for readers to judge whether drug trial results are applicable to clinical decision-making in general practice or when developing clinical guidelines.