Comparative study of pregnancy outcomes in women with inflammatory bowel disease treated with thiopurines and/or anti-TNF: a French nationwide study 2010-2018.
Antoine MeyerJérôme DrouinAlain WeillFranck CarbonnelRosemary Dray-SpiraPublished in: Alimentary pharmacology & therapeutics (2021)
Pregnancies exposed to thiopurines more frequently resulted in stillbirths, preterm births and large for gestational age compared to pregnancies exposed to anti-TNF or unexposed pregnancies. By contrast, pregnancies exposed to anti-TNF monotherapy were not associated with these outcomes.
Keyphrases
- gestational age
- preterm birth
- birth weight
- pregnancy outcomes
- rheumatoid arthritis
- low birth weight
- pregnant women
- magnetic resonance
- type diabetes
- magnetic resonance imaging
- computed tomography
- adipose tissue
- physical activity
- randomized controlled trial
- open label
- preterm infants
- combination therapy
- insulin resistance
- study protocol
- ulcerative colitis
- weight gain