Protein disulfide isomerase a4 promotes lung cancer development via the Stat3 pathway in stromal cells.

Tzung-Yan ChenChun-Yen YangMeng-Ting YangTien-Fen KuoCicero Lee-Tian ChangChih-Li ChenTsung-Han LeeGreta YangWen-Chin YangChing-Feng ChiuAlex Yang-Hao Yu

Published in: Clinical and translational medicine (2022)

These findings identify Pdia4 as a possible target for intervention in cancer stroma, suggesting that targeting Pdia4 in cancer stroma is a promising anti-cancer approach.

Keyphrases

papillary thyroid
squamous cell
randomized controlled trial
cell proliferation
lymph node metastasis
cancer therapy
squamous cell carcinoma
childhood cancer
drug delivery
amino acid