Associations between SARS-CoV-2 variants and risk of COVID-19 hospitalization among confirmed cases in Washington State: a retrospective cohort study.
Miguel I ParedesStephanie M LunnMichael FamulareLauren A FrisbieIan PainterRoy BursteinPavitra RoychoudhuryHong XieShah A Mohamed BakhashRicardo PerezMaria LukesSean EllisSaraswathi SatheesPatrick C MathiasAlexander L GreningerLea M StaritaChris D FrazarErica RykeWeizhi ZhongLuis GamboaMachiko ThrelkeldJover LeeDeborah A NickersonDaniel L BatesMatthew E HartmanEric HaugenTruong N NguyenJoshua D RichardsJacob L RodriguezJohn A StamatoyannopoulosEric ThorlandGeoff MellyPhilip E DykemaDrew C MacKellarHannah K GrayAvi SinghJohnAric MoonDance PetersonDenny RussellLaura Marcela TorresScott LindquistTrevor BedfordKrisandra J AllenHanna N OlteanPublished in: medRxiv : the preprint server for health sciences (2021)
Infection with a VOC results in a higher hospitalization risk, with an active vaccination attenuating that risk. Our findings support promoting hospital preparedness, vaccination, and robust genomic surveillance.