Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.
Jeremy B FooteAbhijit JagdaleTakayuki YamamotoHidetaka HaraMohamed H BikhetHenk-Jan SchuurmanHuy Q NguyenMohamed B EzzelarabDavid AyaresDouglas J AndersonHuma FatimaDevin E EckhoffDavid K C CooperHayato IwasePublished in: Xenotransplantation (2021)
The absence of expression of Neu5Gc on pig kidney grafts is associated with increased binding of baboon antibodies to pig endothelium and reduced graft survival.