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Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.

Jeremy B FooteAbhijit JagdaleTakayuki YamamotoHidetaka HaraMohamed H BikhetHenk-Jan SchuurmanHuy Q NguyenMohamed B EzzelarabDavid AyaresDouglas J AndersonHuma FatimaDevin E EckhoffDavid K C CooperHayato Iwase
Published in: Xenotransplantation (2021)
The absence of expression of Neu5Gc on pig kidney grafts is associated with increased binding of baboon antibodies to pig endothelium and reduced graft survival.
Keyphrases
  • poor prognosis
  • binding protein
  • nitric oxide
  • long non coding rna
  • gas chromatography
  • simultaneous determination