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Evaluation of the molecular origin of amide proton transfer-weighted imaging.

Casey SunYu ZhaoZhongliang Zu
Published in: Magnetic resonance in medicine (2023)
The positive APTw signal using high saturation amplitudes could have significant contributions from soluble proteins through CEST, including amide/amine/guanidine proton transfer effects. In contrast, the negative APTw signal using low saturation amplitudes has significant contribution from lipids through rNOE.
Keyphrases
  • electron transfer
  • magnetic resonance
  • contrast enhanced
  • high resolution
  • magnetic resonance imaging
  • single molecule
  • fatty acid
  • computed tomography
  • network analysis
  • photodynamic therapy