DASS Good: Explainable Data Mining of Spatial Cohort Data.
Andrew WentzelC FloricelGuadalupe CanahuateMohammed A NaserA S MohamedClifton David FullerLisanne V van DijkG Elisabeta MaraiPublished in: Computer graphics forum : journal of the European Association for Computer Graphics (2023)
Developing applicable clinical machine learning models is a difficult task when the data includes spatial information, for example, radiation dose distributions across adjacent organs at risk. We describe the co-design of a modeling system, DASS, to support the hybrid human-machine development and validation of predictive models for estimating long-term toxicities related to radiotherapy doses in head and neck cancer patients. Developed in collaboration with domain experts in oncology and data mining, DASS incorporates human-in-the-loop visual steering, spatial data, and explainable AI to augment domain knowledge with automatic data mining. We demonstrate DASS with the development of two practical clinical stratification models and report feedback from domain experts. Finally, we describe the design lessons learned from this collaborative experience.