Cell-Specific Transposable Element and Gene Expression Analysis Across Systemic Lupus Erythematosus Phenotypes.
Zachary CuttsSarah L PattersonLenka MaliskovaKimberly E TaylorChun Jimmie YeMaria Dall'EraRebecca GraingerLindsey A CriswellGabriela K FragiadakisCharles LangelierJohn A CapraMarina SirotaCristina M LanataPublished in: ACR open rheumatology (2024)
These findings suggest that expression of TEs contributes to activation of SLE-related mechanisms in a cell-specific manner, which can impact disease diagnostics and therapeutics.