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TolRad, a model for predicting radiation tolerance using Pfam annotations, identifies novel radiosensitive bacterial species from reference genomes and MAGs.

Philip SweetMatthew BurroughsSungyeon JangLydia M Contreras
Published in: Microbiology spectrum (2024)
-generated genome annotations to classify a bacterium as tolerant of ionizing radiation (IR) or as radiosensitive. This model allows for rapid screening of bacterial communities for low-tolerance species that are of interest for both mechanistic studies into bacterial sensitivity to IR and biomarkers of IR exposure.
Keyphrases
  • genome wide
  • radiation therapy
  • dna methylation
  • radiation induced