LINC00173.v1 promotes angiogenesis and progression of lung squamous cell carcinoma by sponging miR-511-5p to regulate VEGFA expression.

Jiarong ChenAibin LiuZhihui WangBin WangXingxing ChaiWenjie LuTing CaoRonggang LiMinyan WuZhuming LuWenguang PangLin XiaoXiangmeng ChenYan ZhengQiong ChenJincheng ZengJun LiXin ZhangDong RenYanming Huang

Published in: Molecular cancer (2020)

Our findings clarify the underlying mechanism by which LINC00173.v1 promotes the proliferation and migration of vascular endothelial cells and the tumorigenesis of SQC, demonstrating that LINC00173.v1-targeted drug in combination with cisplatin may serve as a rational regimen against SQC.

Keyphrases

long non coding rna
endothelial cells
poor prognosis
long noncoding rna
squamous cell carcinoma
cell proliferation
vascular endothelial growth factor
high glucose
locally advanced
lymph node metastasis
binding protein
drug delivery
drug induced
electronic health record