Testosterone Treatment, Weight Loss, and Health-related Quality of Life and Psychosocial Function in Men: A 2-year Randomized Controlled Trial.
Mathis GrossmannKristy P RobledoMark DanielDavid J HandelsmanWarrick J InderBronwyn G A StuckeyBu B YeapMark Ng Tang FuiKaren BrackenCarolyn A AllanDavid JesudasonJeffrey D ZajacGary Allen WittertPublished in: The Journal of clinical endocrinology and metabolism (2024)
In this diabetes prevention trial, weight loss induced by a lifestyle intervention improved HR-QOL and psychosocial function in more domains than testosterone treatment. The magnitude of weight and waist circumference reduction were predicted by baseline physical function, depressive symptomology, and sense of coherence.
Keyphrases
- weight loss
- randomized controlled trial
- body mass index
- bariatric surgery
- study protocol
- roux en y gastric bypass
- replacement therapy
- cardiovascular disease
- mental health
- gastric bypass
- physical activity
- glycemic control
- metabolic syndrome
- body weight
- clinical trial
- weight gain
- combination therapy
- skeletal muscle
- adipose tissue
- phase ii
- stress induced
- middle aged
- double blind