Study protocol for a randomised controlled trial of carvedilol versus variceal band ligation in primary prevention of variceal bleeding in liver cirrhosis (CALIBRE trial).

Dhiraj TripathiPeter Clive HayesPaul RichardsonIan RoweJames FergusonPeter DevineJonathan MathersChristopher PoynerSue JowettKelly HandleyMargaret GrantGemma SlinnKhaled AhmedPeter Brocklehurst

Published in: BMJ open gastroenterology (2019)

The study has been approved by a National Health Service (NHS) Research Ethics Committee (REC) (reference number 18/NE/0296). The results of this trial will be submitted for publication in a peer reviewed journal. Participants will be informed via a link to a preview of the publication. A lay summary will also be provided via email or posted to participants prior to publication (ISRCTN reference number: 73887615).

Keyphrases

phase iii
study protocol
phase ii
clinical trial
public health
patient safety
quality improvement
open label
randomized controlled trial
big data
drug administration
deep learning