Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease.

Thomas M JenkinsJames J P AlixJacob FingretTaniya EsmailNigel HoggardKathleen BasterChristopher J McDermottIain D WilkinsonPamela J Shaw

Published in: Journal of neurology (2019)

MUNIX and relative T2-weighted MR represent objective surrogate markers of progressive denervation in MND. Radiological changes were maximal in leg muscles, irrespective of clinical onset-site.

Keyphrases

contrast enhanced
magnetic resonance
multiple sclerosis
skeletal muscle
heart rate
resistance training
magnetic resonance imaging
cross sectional
blood pressure
body composition