Repeated courses of radiation treatment in an HER2-positive breast cancer patient with diffuse brain metastases: A case report.
Sonia SilipigniEdy IppolitoPaolo MatteucciBianca SantoEmma GangemiAnnalisa La CesaDaniele SantiniCarlo GrecoSara RamellaPublished in: The breast journal (2020)
In human epidermal growth factor receptor 2 (HER2+) expressing breast cancer subtype, the incidence of brain metastases is common and patients often die due to uncontrolled cranial disease. This is a case report of a HER2+ breast cancer woman with diffuse brain metastases that experienced long survival and clinical benefit from multiple radiotherapy treatments and combined systemic therapy, without increased toxicity.
Keyphrases
- brain metastases
- small cell lung cancer
- epidermal growth factor receptor
- positive breast cancer
- end stage renal disease
- tyrosine kinase
- ejection fraction
- newly diagnosed
- endothelial cells
- advanced non small cell lung cancer
- case report
- low grade
- chronic kidney disease
- early stage
- prognostic factors
- risk factors
- oxidative stress
- stem cells
- radiation therapy
- induced pluripotent stem cells
- combination therapy
- patient reported outcomes
- pluripotent stem cells
- rectal cancer
- patient reported
- cell therapy