Role of tear exosomes in the spread of herpes simplex virus type 1 in recurrent herpes simplex keratitis.

Huiying HuangSihao LiuXia ZhaoPeiyi ZhaoQingqing JiaHuixiang MaQuankui Lin

Published in: Eye (London, England) (2023)

Tear exosomes should be the latent sites of HSV-1 in recurrent HSK and might be involved in the spread of HSV-1. Besides, this study verifies HSV-1 genes can be indeed transferred between cells by exosomal pathway, providing new inspiration for the clinical intervention and treatment as well as the drug discovery of recurrent HSK.

Keyphrases

herpes simplex virus
drug discovery
mesenchymal stem cells
stem cells
induced apoptosis
randomized controlled trial
cell cycle arrest
gene expression
bone marrow
transcription factor
oxidative stress
cell death
combination therapy
dna methylation