Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial.

Sean M BagshawAry Serpa NetoOrla SmithMatthew WeirHaibo QiuBin DuAmanda Y WangMartin GallagherRinaldo BellomoRon Waldnull null

Published in: Intensive care medicine (2022)

In this secondary analysis of the STARRT-AKI trial, an accelerated strategy of RRT initiation conferred a higher risk of 90-day RRT dependence among patients with pre-existing CKD; however, no effect was observed in the absence of CKD.

Keyphrases

acute kidney injury
chronic kidney disease
phase iii
study protocol
clinical trial
phase ii
randomized controlled trial
open label
adipose tissue
insulin resistance