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Conservative vs liberal fluid therapy in septic shock (CLASSIC) trial-Protocol and statistical analysis plan.

Tine Sylvest MeyhoffPeter Buhl HjortrupMorten Hylander MöllerJørn WetterslevTheis LangeMaj-Brit Nørerregaard KjaerAndreas Bender JonssonCarl Johan Steensen HjortsøMaria CronhjortJon Henrik LaakeStephan M JakobMarek NalosVille PettiläIwan C C van der HorstMarlies OstermannPaul MounceyKathy RowanMaurizio CecconiRicard FerrerManu L N G MalbrainChristian AhlstedtSøren HoffmannMorten Heiberg BestleLars NebrichLene RussellMarianne VangMichael Lindhardt RasmussenChristoffer SøllingBodil Steen RasmussenAnne Craveiro BrøchnerAnders Perner
Published in: Acta anaesthesiologica Scandinavica (2019)
The CLASSIC trial results will provide important evidence to guide clinicians' choice regarding the IV fluid therapy in adults with septic shock.
Keyphrases
  • septic shock
  • study protocol
  • phase iii
  • clinical trial
  • randomized controlled trial
  • palliative care
  • open label
  • cell therapy
  • smoking cessation