Transcriptional signals of transformation in human cancer.

Gerda KildisiuteMaria KalyvaRasa ElmentaiteStijn van DongenChristine ThevanesanAlice PiapiKirsty AmbridgeElena PrigmoreMuzlifah HaniffaSarah A TeichmannKarin StraathofIsidro Cortés-CirianoSam BehjatiMatthew D Young

Published in: Genome medicine (2024)

Our findings provide a nuanced picture of transformation in human cancer, indicating cancer-specific rather than universal patterns of transformation pervade adult epithelial cancers.

Keyphrases

papillary thyroid
endothelial cells
squamous cell
childhood cancer
squamous cell carcinoma
induced pluripotent stem cells
transcription factor
young adults
pluripotent stem cells